Description
CL-218,872(CL-218872) is a non-benzodiazepine drug with sedative and hypnotic effects and is similar in efficacy to triazolam, zolpidem but has a completely different structure.
Chemistry
CL-218,872 a triazolopyridazine, is not a benzodiazepine and has a different structure.
Pharmacology, Pharmacodynamic
According to in vivo studies in mice, this CL-218,872 is a triazolopyridazine that acts at the benzodiazepine binding site; at low doses it has anticonvulsant effects, at higher doses it is sedative and hypnotic. This substance is an agonist of GABA receoters, for subtype α1, 3, 4, 5.
Dosage
The exact dosage is not known, due to the lack of proper medical research.
Medical Applications
CL-218,872 is an investigational drug design.
Legal Status
CL-218,872 has an unclear legal status.
Technical Information:
Product Name CL-218,872
Synonyms CL 218872, CL-218872
IUPAC Name 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
CAS Number 66548-69-4
Molecular Formula C13H9F3N4
Formula Weight 278.23 g/mol
InChi Code InChI=1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3
InChi Key GUOQUXNJZHGPQF-UHFFFAOYSA-N
SMILES CC1=NN=C2N1N=C(C=C2)C3=CC(=CC=C3)C(F)(F)F
Solubility
DMF: 1 mg/ml
DMSO: 1 mg/ml
Ethanol: 1 mg/ml
Formulation A crystalline solid
Purity ≥98%
Disclaimer
CL-218,872 is intended only as a substance for scientific and research purposes under special laboratory conditions in compliance with all standards, safety measures.
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Why buy CL-218,872 online from ChemicalNS company?
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-Product purity is 98-99%.
-You will receive a ZIP Pack, a sealed aluminum foil bag containing the product for research.
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