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LSD. Research on brain neuroplasticity in depression.

The latest scientific data are encouraging: scientists have found that the drug LSD can have a beneficial effect on the white matter of the brain in people suffering from depressive states. The key finding of the study was the discovery of increased organization of...

Dimethyltryptamine (DMT)

Dimethyltryptamine (DMT) is a tryptamine derivative whose molecule includes two additional methyl groups at the position of the nitrogen atom at the amine group. DMT was first isolated from Mimosa root in 1946 by Brazilian ethnobotanist and chemist Goncalves deLima,...

Mechanisms of cellular tolerance to opiates and opioids

Opiates and opioids are opioid receptor agonists. The alkaloids of the opium poppy Papaver somniferum are morphine, codeine, thebaine, oripavine, etc. They are called opiates. The acetylation of alkaloids produces the semi-synthetic opiates diacetylmorphine (heroin),...

Benzodiazepine derivatives

Benzodiazepine derivatives, anxiety–relieving anxiolytics, are called tranquilizers in the old way. Drugs of this group enhance the effects of GABA (gamma-amino-butyric acid), the main inhibitory mediator in the central nervous system. They have a weak effect on...

About dissociative drugs

Phencyclidine (PCP) was synthesized by Parke Davis Co. (USA) and used as a general anesthetic in humans in the last half of the 50s of this century. It was distributed under the name “Sernyl”. The use of PCP put a person into excellent surgical anesthesia...