Avizafone

Description

Avizafone (Avizafone HCL, Pro-Diazepam) It is a sedative and anxiolytic drug, a prodrug of diazepam, for intramuscular administration.
Avizafone is hydrolyzed by aminopeptidase with the release of lysine and diazepam, when administered intramuscularly faster, this drug is metabolized faster in the blood with the release of active diazepam, reaching a higher maximum concentration.
This drug was developed as a remedy for poisoning with nerve agents.
This substance is a preparation for chemical and scientific research aimed at identifying pharmacological, sedative and other properties.

Chemistry

Avizafone is a prodrug of diazepam and has a related structure.

Pharmacology, Pharmacodynamic

Studies of this drug have shown that it affects GABA receptors, causing sedative, anxiolytic, anticonvulsant effects.
Toxicological and pharmacological properties in the process of studying rodents in the laboratory.

Side effects

At high dosages of this drug, a number of side effects have been identified, such as confusion of consciousness, severe intoxication, problems with coordination. The combination of this drug with alcohol, other sedatives and opioid substances is highly dangerous.
If you take the drug regularly, you can develop physical and psychological dependence.

Legal status

Avizafone has an unclear legal status, but in countries where analog drugs are banned, this substance can be considered as an analog of diazepam.

Technical Information:

Product Name Avizafone

Synonyms Avizafone HCL, Pro-Diazepam

IUPAC Name (2S)-2,6-diamino-N-{[(2-benzoyl-4-chlorophenyl)methylcarbamoyl]methyl}hexanamide

CAS Number 65617-86-9

Molecular Formula C22H27ClN4O3

Formula Weight 430.9 g/mol

InChi Code InChI=1S/C22H27ClN4O3/c1-27(20(28)14-26-22(30)18(25)9-5-6-12-24)19-11-10-16(23)13-17(19)21(29)15-7-3-2-4-8-15/h2-4,7-8,10-11,13,18H,5-6,9,12,14,24-25H2,1H3,(H,26,30)/t18-/m0/s1

InChi Key LTKOVYBBGBGKTA-SFHVURJKSA-N

SMILES CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2)C(=O)CNC(=O)C(CCCCN)N

Formulation

Purity ≥98%

Disclaimer of liability

Avizafone is intended only as a substance for scientific and research purposes in special laboratory conditions in compliance with all standards and safety measures.

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